Achaogen(美國)

Achaogen

美國Achaogenwww.achaogen.com2002年，羅姆斯伯格的實驗室剛開始獲得以上結(jié)果時，他就發(fā)現(xiàn)了一種潛在的藥物——能和抗生素一起服用的小分子藥物，該藥物可以阻止LexA受到剪切。他與兩個合伙人毫不費力就籌集到1500萬美元，開辦了一家名叫Achaogen的公司(“Achao”的意思是“抵制混亂”— —并由一位投資者添加上“gen”，因為名稱中具有這個后綴的公司，其發(fā)展往往會一帆風(fēng)順)。Achaogen(a-KAY-o-jen)developssmallmoleculetherapeuticstotreatmulti-drugresistantbacterialinfections,aseriousunmetmedicalneedcausinghundredsofthousandsofdeathsworldwideeachyear.Achaogenisdevelopingnext-generationaminoglycosides:“neoglycosides”—adesignationthatreflectstheirlineageandconveystheirnovelty.Achaogen’sleadneoglycosidesdisplaybroad-spectrumactivityagainstmanyresistantbacteriathatcausesystemicinfections,includingK.pneumoniae,E.coliandMRSA.Ourworld-classteamhasledorparticipatedinthedevelopmentofseveralapprovedand/orlate-stageantibacterialcompounds,andourscientificadvisorsincludeU.