OncoMed(美國)
OncoMed
美國OncoMedwww.oncomed.comOncoMed制藥是一個臨床階段的公司發(fā)現(xiàn)并開發(fā)新型療法,針對癌癥干細胞,細胞認為是能夠驅動腫瘤生長,復發(fā)和轉移。癌癥干細胞研究的,該公司已建立了癌癥干細胞的蛋白質抗體庫的實體腫瘤,如胰腺癌,乳腺癌,腸癌和肺癌的治療。OncoMed已推進到診所指,OMP-21M18-59R5,OMP的,和OMP-18R5,該目標的關鍵癌癥干細胞的信號包括Notch和
Wnt信號通路的三防癌干細胞的單克隆抗體。此外,OncoMed的管道包括了一些新的臨床前候選產(chǎn)品,針對多個驗證癌癥干細胞的途徑。OncoMed與拜耳醫(yī)藥保健制藥和葛蘭素史克公司已形成戰(zhàn)略聯(lián)盟。私人持有,OncoMed的投資者包括:TheVerticalGroup,MorgenthalerVentures,Phase4Ventures,DelphiVentures,AdamsStreetPartners,DeNovoVentures,BayPartnersandGlaxoSmithKline.OncoMedPharmaceuticalsisaclinical-stagecompanythatdiscoversanddevelopsnoveltherapeuticstargetingcancerstemcells,thecellsbelievedtobecapableofdrivingtumorgrowth,recurrenceandmetastasis.Aleaderincancerstemcellresearch,thecompanyhasestablishedalibraryofantibodiestocancerstemcellproteinsforthetreatmentofsolidtumorssuchaspancreatic,breast,colorectalandlungcancers.OncoMedhasadvancedthreeanti-cancerstemcellmonoclonalantibod